Krusiec was recruited to be one of six globe-trotting travel reporters for the Discovery Channel series Travelers in 1996. Along with Barbara Alvarez, Robin Kipp, Pearce Bunting, Patrick Michael, Foster Soloman, and later Lisa Clark, she traveled to over 50 different locations on the show. Krusiec played the 18-year-old Molly O'Brien in the Star Trek: Deep Space Nine episode "Time's Orphan". She co-starred in the NBC Saturday morning sitcom One World and played the role of Exquisite Woo on Popular. She played Mei-Ling Hwa Darling, one of the Darling family's daughters-in-law, in ABC's dramedy, Dirty Sexy Money. She appeared in The Mind of the Married Man as Sachiko, a massage parlor employee. She had a recurring role as "Nadine Park" on Season 4 of Fox's Fringe, and has also appeared on TV shows such as NBC's Community as "Wu Mei", a love interest of Chevy Chase's character, Pierce Hawthorne, General Hospital as Attorney Grace Yang, The Secret Life of the American Teenager as Emily, Touch as Lanny Cheong, Nip/Tuck as Mei, CSI: Miami as Susan Lee, CSI: NY as Lisa Kim, NCIS, Grey's Anatomy, Weeds, Without A Trace, Cold Case as Kara, Monk as Maria, ER as Tong-Ye, and Titus as recurring character Nancy.
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